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光遗传病毒

光遗传激活病毒列表

文字:[大][中][小] 2016-10-15    浏览次数:1980    
光遗传激活工具 病毒特点
AAV-CaMKIIa-hChR2(H134R)-mCherry CaMKIIa启动子(部分脑区为兴奋性神经元特异启动子);使用最普遍的ChR2,激发波长470 nm
AAV-CaMKIIa-hChR2(H134R)-EYFP
AAV-hSyn-hChR2(H134R)-EYFP hSyn神经元特异启动子;
AAV-hSyn-hChR2(H134R)-mCherry
AAV-CAG-hChR2(H134R)-tdTomato  CAG非特异强启动子
AAV-CAG-ChR2-GFP
AAV-CMV-bGI-hChR2(H134R)-mCherry CMV非特异强启动子
AAV-EF1a-double floxed-hChR2(H134R)-mCherry Cre依赖;Ef1α非神经元特异强启动子;使用最普遍的ChR2,激发波长470 nm
AAV-EF1a-double floxed-hChR2(H134R)-EYFP
AAV-EF1a-fDIO-hChR2(H134R)-EYFP flp依赖
AAV-nEF-Con/Fon-hChR2(H134R)-EYFP Cre或者Flp开启表达;nEF启动子
AAV-hSyn-Con/Foff-hChR2(H134R)-EYFP  Cre开启,Flp关闭表达
AAV-hSyn-Con/Fon-hChR2(H134R)-EYFP Cre或者Flp开启表达
AAV-hSyn Coff/Fon hChR2(H134R)-EYFP Cre关闭,Flp开启表达
AAV-Ef1a-DIO C1V1 (t/t)-TS-EYFP  C1V1 (t/t)ChR1VChR1(ChR的突变体)组成的杂合体,激发光波长560 nm
AAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry
AAV-CaMKIIa-C1V1(t/t)-TS-EYFP
AAV-CaMKIIa-C1V1 (t/t)-TS-mCherry
AAV-CaMKIIa-hChR2(E123A)-EYFP hChR2(E123A)ChETA(A)是点突变的ChR2,适合高频激活,激活波长470 nm
AAV-CaMKIIa-hChR2(E123A)-mCherry 
AAV-Ef1a-DIO ChETA-EYFP Cre依赖ChETA
AAV-CaMKIIa-hChR2(E123T/T159C)-EYFP hChR2(E123T/T159C)ChETA(TC)是突变的ChR2,适合高频激活,激活波长470 nm
AAV-CaMKIIa-hChR2(E123T/T159C)-mCherry
AAV-hSyn-oChIEF-tdTomato CHIEFChR1ChR2的杂合体,可用于高频刺激,激活波长470 nm
AAV-Flex-rev-oChIEF-tdTomato Cre依赖CHIEF
AAV-hSyn-FAS-DO-ReaChR-mCitrine ReaChRChEF/ChIEF,VChR1,VChR2外加L171I突变组成,激发波长590-630 nm
AAV-Syn-ChrimsonR-GFP 天然存在的CnChR1(Chrimson)K176R点突变,激发波长590 nm
AAV-hSyn-ChrimsonR-tdTomato
AAV-CaMKIIa-ChrimsonR-tdTomato
AAV-CaMKIIa-ChrimsonR-GFP
AAV-Syn-FLEX-rc[ChrimsonR-tdTomato] Cre依赖的ChrimsonR
AAV-CaMKII-Chronos-GFP 天然存在的ShChR(Chronos),激发波长530 nm
AAV-Syn-Chronos-GFP
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